Hundreds of gene regulatory motifs cooperate and conflict to make brain cells - Phys.org

DNA is considered the blueprint of our human bodies. It codes for the tens of thousands of genes that determine whether a cell transforms into a brain cell, heart cell or even cancer cell. Other DNA sequences, known as enhancers, determine if genes are activa…

Experimental design. a Computational framework to select regions and perturbation sites. b Heatmap of motif instances in the assayed regions (left); distribution of the number of motifs perturbed in … [+5262 chars]

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