Anatomic position determines oncogenic specificity in melanoma - Nature.com

3/30/2022 12:00:00 AM3 years 10 months ago

In a zebrafish model of human cutaneous and acral melanomas, CRKL amplification causes tumours to favour a fin location, indicating that tumour location is determined by both the driver oncogenes and the pre-existing positional identity gene pr…

  • Tang, J. et al. The genomic landscapes of individual melanocytes from human skin. Nature586, 600605 (2020). ADS  CAS  PubMed  PubMed Central  Google Scholar 
  • Fowler, J. C. et al… [+19339 chars]

    full article...