A panel of nanobodies recognizing conserved hidden clefts of all SARS-CoV-2 spike variants including Omicron | Communications Biology - Nature.com

A panel of nanobodies are presented that can detect the spike proteins of five SARS-CoV-2 variants of concern and structural analyses show that one clone targets conserved epitopes on the receptor-binding domain and contacts the N-terminal domain.

Ethics statement for animal care and informed consent Two young alpacas (Vicugna pacos) half-siblingsa 19-month-old male named Puta and a 19-month-old female named Christywere immunized. Veterinaria… [+37814 chars]

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