Integrating cell morphology with gene expression and chemical structure to aid mitochondrial toxicity detection | Communications Biology - Nature.com

Cell Painting, gene expression, and chemical structural data are used to examine the differences between mitochondrial toxicants and non-toxicants and enhance the detection of mitotoxic compounds for future drug discovery.

Dykens, J. A., Marroquin, L. D. & Will, Y. Strategies to reduce late-stage drug attrition due to mitochondrial toxicity. Expert Rev. Mol. Diagn.7, 161175 (2007). CAS  PubMed  Article  G… [+22700 chars]

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